Progesterone in Women with Bleeding in Early Pregnancy: Absence of Evidence, Not Evidence of Absence

Available on https://psyarxiv.com/etk7g/, this is a comment on a recent article in the New England Journal of Medicine (Coomarasamy et al., 2019). A response by the authors will follow at a later point. A recent trial assessed the effectiveness of progesterone in preventing miscarriages.1 The number of live births was 74.7% (¹⁵¹³⁄₂₀₂₅) in the progesterone …