Part 4 CITE-seq normalization using empty droplets with the dsb package

In this post, we are going to try a CITE-seq normalization method called dsb published in Normalizing and denoising protein expression data from droplet-based single cell profiling

two major components of protein expression noise in droplet-based single cell experiments: (1) protein-specific noise originating from ambient, unbound antibody encapsulated in droplets that can be accurately …