Introduction

Human papilloma virus (HPV) is known to be an important factor in the development of invasive cervical cancer and other malignant and bening neoplastic lesions, affecting the vulva, vagina, anus, penis, head/neck, lungs and external genital area. Vaccination against particular strains of HPV has been recently made available; however, the actual cost-effectiveness of vaccination strategies (specifically, in our case, using the quadrivalent vaccine, which acts against 4 HPV strains) is generally subject to large …