HRGM2：涵盖 41 个国家的的人类肠道MAGs目录，支持基因组规模代谢模型

2025-12-15

人类肠道微生物组研究依赖于全面的基因组目录，然而现有资源存在地理多样性不足和基因组质量不高的问题。许多目录包含中等质量的宏基因组组装基因组（MQ MAGs），这些基因组可能缺失高达50%的基因组区域，从而扭曲功能分析结果。

Ma, J., Kim, N., Cha, J.H. et al. A human gut metagenome-assembled genome catalogue spanning 41 countries supports …

生态系统健康塑造泥炭地土壤中的病毒生态|Nature Microbiology

2025-12-15

泥炭地储存了地球土壤碳的三分之一，但由于人类活动的影响，正从碳汇转变为碳源。恢复工作旨在逆转这一趋势，但病毒对泥炭地恢复的影响尚不明确，尽管病毒是微生物组和生态系统功能的重要调节因子。

Kosmopoulos, J.C., Pallier, W., Malik, A.A. et al. Ecosystem health shapes viral ecology in peatland soils. Nat …

ResMicroDb：人类呼吸道微生物组综合数据库与分析平台

2025-12-15

呼吸道微生物组在维持人体健康中扮演着重要角色。尽管相关文献和公共数据快速增长，目前仍缺乏大规模、高质量注释的呼吸道微生物组数据库。ResMicroDb整合了来自514个项目的106,464个样本，覆盖10个采样部位、72种样本类型和146种表型，并提供了标准化分析流程生成的物种注释谱、手动整理的32项元数据字段，以及基于132项病例对照研究鉴定的11,908条微生物-疾病关联。平台还集成了微生物组成可视化、样本相似性搜索和跨研究分析三大工具，支持用户深入探索呼吸道微生物组的分布特征与健康关联。ResMicroDb旨在推动呼吸道微生物组的基础研 …

AI-generated recaps pulled by Amazon Prime Video

2025-12-15

For the show Fallout, Amazon Prime Video was testing AI-generated episode recaps, but…

Tags: Amazon, Fallout, Verge

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McDonald’s pulls AI-generated commercial, because terrible

2025-12-15

McDonald’s Netherlands put up a commercial that was generated with AI and it…

Tags: commercial, Futurism, McDonald’s

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III Congreso Universitario Internacional sobre Seguros y Reaseguros en Perú

2025-12-15

In a few hours, I will give a talk at the III Congreso Universitario Internacional sobre Seguros y Reaseguros en Perú, I will give a talk on “Detecting Hidden Bias in Insurance AI Through Counterfactuals” As AI becomes embedded in underwriting, pricing, fraud detection, and claims automation, one challenge remains widely underestimated: models can discriminate without ever using a prohibited variable. Indirect discrimination (i.e., bias transmitted through correlated or downstream variables) poses a subtle but critical risk for insurers, all the more since actuarial … <a …

Balance and calibration in insurance

2025-12-15

Tomorrow morning, I will give a lecture online on Balance, Calibration and Related Concepts, for actuaries, working in an insurance company. We will start with calibration We will also discuss Lorenz and Concentration …

Qui doit payer un risque lié à une défaillance de maintien de l’ordre ?

2025-12-15

Un petit sujet polémique avant les fêtes ? Parlons un peu d’assurance et de maintien de l’ordre… Depuis les violences urbaines de ces dernières années, la question de “comment indemniser les émeutes” s’est invitée dans le débat public au point d’entrer au Sénat, sous la forme d’un projet de régime adossé aux contrats d’assurance de “dommages aux biens”, avec une garantie obligatoire, une surprime et un mécanisme de mutualisation au-delà de certains seuils. Dans l’hémicycle, on a un débat assez classique, les sénateurs voulant rendre … <a href=“https://freakonometr …

Better Code, Without Any Effort, Without Even AI

2025-12-15

We are experiencing a programming revolution, with the democratization of artificial intelligence, but also with the creation and improvement of more traditional software tools to improve your code: local, free, deterministic. In this post, we will introduce you to <ul> <li>📦 <a href="https://lintr.r-lib.org/">lintr</a>, by <a href="https://lintr.r-lib.org/authors.html">Michael Chirico and many others</a>, an R package that detects many ways to improve your …

Simulating from and checking a model in Stan: It’s so easy in Stan Playground–it just runs on your browser!

2025-12-15

When building models, it’s helpful to check our understanding by simulating fake data and seeing if the fitted model can recover the true underlying parameters. And it’s so easy to do in Stan! See above–I just did a simple example … Continue reading → …

Who is the most famous living person who was born on each continent?

2025-12-15

Matt Larson writes: Because of your interest in fame [see here, here, here, and, especially, here — ed.], I would be interested in your thoughts on the following questions: who is the most famous living person who was born on … Continue reading → …

Better Code, Without Any Effort, Without Even AI

2025-12-15

We are experiencing a programming revolution, with the democratization of artificial intelligence, but also with the creation and improvement of more traditional software tools to improve your code: local, free, deterministic.
In this post, we will in…

Continue reading: Better Code, Without Any Effort, Without Even …

Elephant(s) in the room: Graph neural networks, embeddings, and foundation models in spatial data science

2025-12-15

Slides: https://jakubnowosad.com/agforum2025
This presentation covered three interconnected deep learning concepts appearing in spatial data science work.
Graph Neural Networks (GNNs) are a deep learning architecture that represents spatial dat…

Continue reading: <a href=“https://www.r-bloggers.com/2025/12/elephants-in-the-room-graph-neural-networks-embeddings-and-foundation-models-in-spatia …

R Package Development in Positron workshop

2025-12-15

Join our workshop on R Package Development in Positron, which is a part of our workshops for Ukraine series! Here’s some more info: Title: R Package Development in Positron Date: Thursday, January 15th, 18:00 – 20:00 CET (Rome, Berlin, Paris timezone) Speaker: Stephen D. Turner is an associate professor of data science …

Continue reading: R Package Development in Positron …

Set Operations with freeCount

2025-12-15

In general, set operations are very useful for comparing lists of things. These lists can contain any strings, such as gene or species names. Set operations are also a good way to identify unique or shared genes across sets of analysis results. The freeCount SO app will help you perform …

Continue reading: Set Operations with …

Dify 建立问数流程

2025-12-15

NA …